| Unlockable | How to Unlock |
| Xavier Institute (0 points) | Complete Iceman's training mission. |
| Xavier Institute (0 points) | Complete Nightcrawler's training mission. |
| Xavier Institute (0 points) | Complete Wolverine's training mission. |
| Danger Room Challenge for Iceman (20 points) | Complete Act 1. |
| Danger Room Challenge for Nightcrawler (20 points) | Complete Act 2. |
| Danger Room Challenge for Wolverine (30 points) | Complete Act 3. |
| Evolution For Iceman (125 points) | Upgrade Iceman with all available mutations. |
| Evolution For Nightcrawler (125 points) | Upgrade Nightcrawler with all available mutations. |
| Evolution For Wolverine (120 points) | Upgrade Wolverine with all available mutations |
| Champion For Iceman (70 points) | Collect all Sentinel Tech as Iceman. |
| Champion For Nightcrawler (70 points) | Collect all Sentinel Tech as Nightcrawler. |
| Champion For Wolverine (110 points) | Collect all Sentinel Tech as Wolverine. |
| Secret Identity For Iceman (70 points) | Collect all Weapon X Files as Iceman. |
| Secret Identity For Nightcrawler (80 points) | Collect all Weapon X Files as Nightcrawler. |
| Secret Identity for Wolverine (110 points) | Collect all Weapon X Files as Wolverine. |
| X-Men (50 points) | Accumulate a 950 achievement score. |
